真实 勾引 导师简介——段贤春
真实 勾引
段贤春,男,1981年7月出身,博士,副西宾,副主任药师,硕士生导师,安徽省学术和时代带头东说念主后备东说念主选,主要从事中药药理学谈论。主握国度当然科学基金面上神气、安徽省当然科学基金后生神气等千般科研课题10余项,以第一作家或通信作家发表论文30余篇(SCI收录15篇);获安徽省当然科学二等奖1项、中华中医药学会科技最初三等奖1项,国度发明专利1项(第一专利权东说念主);参编高档中医药院校诡计课本3部、学术著述5部(其中1部为副主编)、蚁集药理学谈论才气标准1部,获得省级科研遵守7项。多年来主要围绕中药复方物资基础及作用机制开展联系探索,松懈凝练出以下谈论标的:(1)中药复方蚁集药理学与系统生物学谈论;(2)中医药防治缺血性中风的作用及机制谈论;(3)病院药学谈论。
1、主要社会兼职情况
现任寰球中医药学汇聚合会蚁集药理学专科委员会常务理事、副文书长,中华中医药学会后生委员、中华中医药学会中药履行药理分会后生委员,安徽省药理学会理事,安徽省药学会病院药学专科委员会文书长。同期担任《江苏大学学报》(医学版)、《中国药房》(蚁集版)编委,Journal of Ethnopharmacology、Frontiers in Pharmacology、Journal of Separation Science、BioMed Research International等学术期刊审稿众人,国度当然科学基金神气函审众人。
2、频年来主握科研神气情况
(1)国度当然科学基金面上神气/基于circDnajc1/miR-27a-5p/C1qc信号轴斟酌小胶质细胞活化在缺血性中风神经元凋一火中的作用及桃红四物汤调控机制/2021年1月~2024年12月/55万/主握;
(2)安徽高校省级当然科学谈论(重心)神气/基于蚁集药理学谈论桃红四物汤防治缺血性中风主要物资基础及作用机制/2019年7月~2021年6月/6万/主握;
(3)安徽省栽植厅/高校优秀拔尖东说念主才培育神气/2019年7月~2021年6月/3万/主握;
(4)安徽省当然科学基金后生神气/基于PICK1卵白与GluR2亚基谈论三七超临界萃取物神经保护作用及机制/2015年1月~2016年12月/7万/主握;
(5)安徽高校省级当然科学谈论(重心)神气/基于PICK1卵白调控AMPA受体谈论东说念主参炔醇神经保护作用偏激机制/2014年1月~2015年12月/5万/主握;
(6)安徽省省级中医发展专项经费神气/芪贞降糖颗粒质地收尾及主要药效学谈论/2014年1月~2015年12月/5万/主握;
(7)安徽省康缘中医药科技鼎新基金神气/诊治围绝经期轮廓征的紫参胶囊研制配置/2010年1月~2011年12月/10万/主握真实 勾引。
3、频年来发表有代表性学术论文
[1]Ni Wang, Furui Chu, Lijuan Zhang, Changyi Fei, Chao Yu, Sujun Xue, Yongzhong Wang, Ling Fang, Daiyin Peng, Xianchun Duan*, and Weidong Chen*. Taohong siwu decoction attenuates AIM2 and NLRC4 inflammasomes by ameliorates deoxyribonucleic acid damage after ischemic stroke. Frontiers in Pharmacology. 2022. 13: p. 954867.(通信作家)
[2]Lingyu Pan, Can Peng, Lei Wang, Lili Li, Shi Huang, Changyi Fei, Ni Wang, Furui Chu, Daiyin Peng, Xianchun Duan*. Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu Decoction against ischemic stroke. Journal of Ethnopharmacology. 2022. 294: p. 115339.(通信作家)
[3]Ni Wang, Furui Chu, Changyi Fei, Lingyu Pan, Yongzhong Wang, Weidong Chen, Daiyin Peng, Xianchun Duan*, Ling He*. Naoluo Xintong decoction in the treatment of ischemic stroke: A network analysis of the mechanism of action. Frontiers in Pharmacology. 2022. 13: p. 809505.(通信作家)
[4]Shi Huang, Yan Chen, Lingyu Pan, Changyi Fei, Ni Wang, Furui Chu, Daiyin Peng, Xianchun Duan*, Yongzhong Wang*. Exploration of the Potential Mechanism of Tao Hong Si Wu Decoction for the Treatment of Breast Cancer Based on Network Pharmacology and In Vitro Experimental Verification. Frontiers in Oncology. 2021. 11: p. 731522.(通信作家)
科目三 裸舞[5]Ni Wang, Changyi Fei, Furui Chu, Shi Huang, Lingyu Pan, Daiyin Peng, Xianchun Duan*. Taohong Siwu Decoction Regulates Cell Necrosis and Neuroinflammation in the Rat Middle Cerebral Artery Occlusion Model. Frontiers in Pharmacology. 2021. 12: p. 732358.(通信作家)
[6]Xinkui Liu, Yang Wu, Yingying Zhang, Dechao Bu, Chao Wu, Shan Lu ,Zhihong Huang, Yurong Song, Yi Zhao, Fengying Guo, Peizhi Ye, Changgeng Fu, Liangliang Shen, Jingyuan Zhang, Haojia Wang, Xianchun Duan*, Jiarui Wu*. High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer.Frontiers in Oncology. 2021. 11:p.747300.(通信作家)
[7]Taohua Wei, Wenjie Hao, Lulu Tang, Huan Wu, Shi Huang, Yue Yang, Nannan Qian, Jie Liu, Wenming Yang* and Xianchun Duan*. Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan-Dou-Fu-Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model. Frontiers in Pharmacology. 2021. 12: p. 622268(通信作家)
[8]Xianchun Duan, Lingyu Pan, Qiuyu Bao, Daiyin Peng*. UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment. Frontiers in Pharmacology. 2019. 10: p. 1625.(第一作家)
[9]Xianchun Duan, Lingyu Pan, Daiyin Peng, Qiuyu Bao, Ling Xiao, An Zhou, Huan Wu, Can Peng, Weidong Chen. Analysis of the active components and metabolites of Taohong Siwu decoction by using ultra high performance liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of separation science.2020. 43(22): p. 4131-4147.(第一作家)
[10]Xianchun Duan, Lan Han, Daiyin Peng, Can Peng, Ling Xiao, Qiuyu Bao, Huasheng Peng. Bioinformatics analysis of a long non-coding RNA and mRNA regulation network in rats with middle cerebral artery occlusion based on RNA sequencing. Molecular medicine reports. 2019. 20(1): p. 417-432.(第一作家)
[11]Xianchun Duan, Lili Li, Jianghua Gan, Can Peng, Xiaoli Wang, Weidong Chen, Daiyin Peng*. Identification and functional analysis of circular RNAs induced in rats by middle cerebral artery occlusion. Gene. 2019. 701: p. 139-145.(第一作家)
[12]Xianchun Duan, Jianghua Gan, Daiyin Peng*, Qiuyu Bao, Ling Xiao, Liangbing Wei, Jian Wu. Identification and functional analysis of microRNAs in rats following focal cerebral ischemia injury. Molecular Medicine Reports. 2019. 19(5): p. 4175-4184.(第一作家)
[13]Xianchun Duan, Jianghua Gan, Fan Xu, Lili Li, Lan Han, Can Peng, Qiuyu Bao, Ling Xiao, Daiyin Peng*. RNA Sequencing for Gene Expression Profiles in a Rat Model of Middle Cerebral Artery Occlusion. Biomed Research International, 2018. 2018: p. 2465481.(第一作家)
[14] Xianchun Duan, Lan Han, Daiyin Peng*, Weidong Chen, Can Peng, Ling Xiao, Qiuyu Bao. High Throughput mRNA Sequencing Reveals Potential Therapeutic Targets of Tao-Hong-Si-Wu Decoction in Experimental Middle Cerebral Artery Occlusion. Frontiers in Pharmacology. 2018. 9: p. 1570.(第一作家)
[15]Xianchun Duan, Jianpeng Hu, Yongzhong Wang, Jiarong Gao, Daiyin Peng*, Lunzhu Xia*. MicroRNA-145: a promising biomarker for hepatocellular carcinoma (HCC). Gene. 2014. 541(1): p. 67-8.(第一作家)
[16]段贤春,黄石,彭代银,韩岚,汪小莉,汪永忠,潘凌宇.蚁集药理学在中药复方谈论中的运用[J].中国药理学通报,2020,36(03):303-308.
[17]段贤春,周安,彭代银,鲍金云,夏伦祝.三七超临界CO2萃取物对谷氨酸挫伤PC12细胞的保护作用[J].中国药理学通报,2017,33(12):1685-1690.
4、交流谈论生情况
实现业获学位硕士生6东说念主,现在在读7东说念主。
5、有计划神气
Email: duanxc@ahtcm.edu.cn
地址:合肥市蜀山区梅山路117号安徽中医药大学第一附属病院